Inhibition of platelet aggregation by transdermal glyceryl trinitrate.
نویسندگان
چکیده
منابع مشابه
Inhibition of platelet aggregation by transdermal glyceryl trinitrate.
OBJECTIVE To determine the optimum conditions for the demonstration of an antiplatelet effect of nitric oxide and to use these conditions to elucidate the effects of a transdermal glyceryl trinitrate patch on platelet aggregation in normal volunteers. METHODS An open prospective crossover study. The effects of nitric oxide on platelet aggregation in whole blood and platelet rich plasma as sti...
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Xanthine oxidoreductase (XOR) is a mammalian enzyme that possesses a series of redox centers, which use either NAD(+) or molecular oxygen for oxidation of the purines xanthine and hypoxanthine to uric acid. The ability of XOR to act as an NADH oxidase is a less well recognized function of the enzyme, and it is this function that we used to explore the metabolism of glyceryl trinitrate. The anti...
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Brazil 13 14 #Corresponding author: Leonardo JM Carvalho, La Jolla Bioengineering Institute, 3535 15 General Atomics Court, Suite 210, San Diego, CA, 92121, USA, Telephone:1−858−456−7500, 16 Fax:1−858−456−7540, Email: [email protected] 17 18 AAC Accepts, published online ahead of print on 26 August 2013 Antimicrob. Agents Chemother. doi:10.1128/AAC.00488-13 Copyright © 2013, American Society f...
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The effect of intra-carotid arterial infusions of glyceryl trinitrate (GTN), a substance known to precipitate headache, including migraine, upon the spontaneous activity of trigeminal neurons with craniovascular input was studied in cats. Second-order craniovascular neurons which received sensory input from the superior sagittal sinus were recorded in the trigeminal nucleus caudalis. Infusions ...
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ژورنال
عنوان ژورنال: Heart
سال: 1994
ISSN: 1355-6037
DOI: 10.1136/hrt.72.6.575